Procalcitonin (PCT) is a glycoprotein with no hormone activity discovered by Assicot et al. in 1993. It is mainly produced under the stimulation of bacterial toxins and inflammatory cytokines, and generally does not increase under non-infectious inflammation. . At present, it has been used as an important indicator to distinguish bacteria and sepsis at home and abroad.
PCT concentration (ng/ml) | Clinical significance | Disposal suggestions |
<0.05 | Normal value | |
0.1~0.25 | Bacterial infection is unlikely | Antibiotics are not recommended |
0.25~0.5 | No or mild systemic inflammation, which may be local inflammation or local infection | It is recommended to find infections or other causes of increased PCT, and antibiotics are recommended |
0.5~2 | Moderate systemic inflammation, infection may exist, or other conditions, such as inflammatory trauma, major surgery, cardiogenic shock | It is recommended to look for possible infection factors. If infection is found, it is recommended to review the PCT after 6-24 hours. |
2-10 | It is likely to be sepsis, severe sepsis, or septic shock, with a high risk of organ dysfunction | It is recommended to review the PCT daily. If the PCT continues to be high (>4d): Reconsider the sepsis treatment plan. |
≧10 | Almost all are severe sepsis or septic shock, often accompanied by organ failure, with a high risk of death | It is recommended to monitor PCT daily to evaluate the treatment effect |
Detection range | sample size | Sample type | Test time |
0.1~100ng/mL | 60μl | Whole blood / serum / plasma | 15min |
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
The company has always adhered to the core concept of "fast and accurate, living up to life", committed to providing society with excellent products and services, and contributing to the cause of human health.