Procalcitonin (PCT) is a non hormonal glycoprotein discovered by assicot et al. In 1993. It is mainly produced under the stimulation of bacterial toxins and inflammatory cytokines, and does not increase in non infectious inflammation. At present, it has been used as an important indicator to identify bacteria and sepsis at home and abroad.
PCT concentration (ng/ml) | Clinical significance | Disposal suggestions |
<0.05 | Normal value | |
0.1~0.25 | Bacterial infection is unlikely | Antibiotics are not recommended |
0.25~0.5 | No or slight systemic inflammatory response, caused by local inflammation or local infection. | Antibiotics should be used for PCT caused by infection or other reasons. |
0.5~2 | Inflammation in the medium system may be infection or other diseases, such as injury, inflammation, major surgery. Cardiac shock | If there are possible infection factors, it is recommended to check PCT six hours after. |
2-10 | Most likely sepsis, severe sepsis or septic shock, with a high risk of organ dysfunction | It is recommended to review PCT daily. If PCT continues to be high (>4d): reconsider the treatment of sepsis |
≧10 | Almost all of them are severe sepsis or septic shock, often accompanied by organ failure, with a high risk of death | It is suggested that PCT should be monitored daily to evaluate the therapeutic effect |
Detection range | sample size | Sample type | Test time |
0.1~100ng/mL | 60μl | Whole blood / serum / plasma | 15min |
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
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