FSH, also known as follicle stimulating hormone, is secreted by the pituitary gland. For women, its main function is to promote the development and maturation of ovarian follicles. In cooperation with luteinizing hormone (LH), FSH promotes the mature follicles to secrete estrogen and ovulate, and participates in the formation of normal menstruation. For the treatment of infertility is of great significance, generally 5 ~ 40 mIU / ml as the normal value. Low FSH values were found in the period of estrogen and progesterone treatment, polycystic syndrome, Sheehan's syndrome, etc., while high FSH values were found in premature ovarian failure, ovarian hypoplasia, pituitary precocious puberty, primary amenorrhea, etc.
Dynamic monitoring of FSH peak changes in follicular phase and accurate evaluation of ovarian function
Assisted diagnosis of reproductive endocrine diseases such as amenorrhea, menopause, premature ovarian failure (POF), ovulation mechanism disorder, etc
Corresponding items | Indicators | Guiding significance | |
FSH,LH | ↑ | It is common in primary lesions of gonad | For example, premature ovarian failure, gonadal insufficiency, primary amenorrhea, primary hypofunction, DYSDEVELOPMENT of spermatogonia, completeness (authenticity) precocious. |
↓ | It is mainly seen in pituitary or hypothalamic amenorrhea, incomplete (pseudo) precocious puberty. | ||
Pituitary FSH tumor or LH tumor | The concentration of FSH and LH changed in different types of tumors | FSH tumor mainly showed increased FSH and normal LH; In patients with LH tumor, LH increased significantly and FSH decreased; | Both FSH and LH were increased in FSH / LH tumors. |
Concentration of FSH and LH in amenorrhea women | To differentiate ovarian amenorrhea from pituitary or hypothalamic amenorrhea |
Detection range | sample size | Sample type | Test time |
0.2~160mIU/mL | 60μl | Whole blood / serum / plasma | 15min |
Gynecology, obstetrics, laboratory, oncology, reproductive medicine, genetics, etc
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