B-type natriuretic peptide is also called brain natriuretic peptide. BNP is mainly synthesized and secreted by ventricular myocytes. Changes in ventricular load and wall tension are the main conditions for stimulating BNP secretion. BNP can promote sodium excretion and urination, and has a strong vasodilator effect. The level of B-type natriuretic peptide is usually significantly increased in patients with atrial fibrillation and heart failure. At present, BNP is one of the most common heart failure biomarkers in clinical use
Detection range | sample size | Sample type | Test time |
5~5000pg/mL | 60μl | Plasma / whole blood | 15min |
BNP | Clinical application recommendations |
<100pg/mL | HF is very unlikely |
100-400pg/mL | Heart failure may be low, combined with other clinical manifestations to diagnose |
>400pg/mL | HF is likely |
Cardiology, emergency department, Nephrology, respiratory medicine, etc
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