Troponin I Detection Reagent(CTnI) (Immunofluorescence Chromatography) Clinical Significance

CTnI Overview

Troponin I (cTnI) is a unique protein of cardiomyocytes, which can significantly regulate the contraction of cardiomyocytes. It is widely used in the clinical detection of myocardial injury and unstable angina pectoris. After the onset of such patients, cTnI appears early, lasts for a long time, has the advantages of myocardial specificity and long diagnostic window period, and is the preferred marker for the diagnosis of myocardial infarction

CTnI Performance Index

CTnI Clinical Significance

• The preferred marker for the diagnosis of myocardial infarction (MI)
• The infarct size was measured and risk stratified
• Diagnosis of prognosis in patients with AMI

Access to diagnosis and risk stratification of ACS (ESC guidelines 2007)

See a doctor	Chest pain/chest tightness
Medical history and physical examination	Suspected ACS (Acute Coronary Syndrome)
electrocardiogram	Persistent ST segment elevation	Abnormal St/T segment ↓		ECG normal ↓
Biochemical test	↓Confirm	CTN was positive		Troponin CTN negative ×2
Risk stratification		high-risk		Low risk
diagnosis	ST-segment elevation myocardial infarction STEMI	Non-ST-segment elevation myocardial infarction NSTEMI		Unstable angina pectoris UA
treatment	Reperfusion	Interventional therapy		Non-interventional therapy

CTnI Advantages of clinical application

• Smaller molecular weight and longer duration
• The concentration was highly correlated with the degree of damage

CTnI Reference

cTnT <0.1 μg/L is normal;> 0.2 μg/L is the diagnostic cut-off value;> 0.5 μg/L can be diagnosed as acute myocardial infarction; cTnI <0.2 μg/L is normal;> 1.5 μg/L is the diagnostic cut-off value ( Using ELISA method)

Application Department

Cardiology, emergency, laboratory, pediatrics, hematology, oncology, Nephrology, surgery, etc

Clinical comparison of cTnI

Company profile

Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
The company has always adhered to the core concept of "fast and accurate, living up to life", committed to providing society with excellent products and services, and contributing to the cause of human health.