D-dimer (D-dimer) is an important marker associated with acute thrombus, and its elevation reflects the phenomenon of increased coagulation and fibrinolytic activity in vivo. It is a kind of indicator that not only reflects the existence or continuous formation of thrombus in vivo, but also reflects the enhancement of fibrinolytic activity in vivo. Among the fibrin degradation products, D-dimer can reflect the thrombolytic activity after thrombus formation, which is of great importance for the diagnosis and treatment of clinical thrombotic diseases.
Detection range | sample size | Sample type | Test time |
0.1~10mg/L | 60μl | Whole blood / plasma | 5min |
Acute thrombus forms in the circulatory system | ||
vein | artery | Microvascular circulation |
Deep vein thrombosis (DVT) | Acute coronary syndrome (ACS) apoplexy | Disseminated intravascular coagulation (DIC) |
Different reagents have different ranges of normal values, generally <0.3mg/L or <0.5mg/L.
Laboratory, cardiology, ICU, emergency department, pediatrics, operating room
Outpatient with venous thromboembolism | |||
Clinical preassessment | |||
Low/moderately suspicious | Highly suspicious | ||
D-Dimer<0.5mg/L | D-Dimer≧0.5mg/L | ||
Thromboembolism was excluded | Thromboembolism is suggested and further examination is required | ||
Do not need treatment | Clinical auxiliary examination | ||
No thrombosis | thrombosis | ||
Do not need treatment | treatment |
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