Creatine Kinase Isoenzyme Detection Reagent(CK-MB) (Immunofluorescence Chromatography) Clinical Significance

CK-MB Overview

Creatine kinase isoenzyme (CK-MB) is an enzyme system that widely exists in human rhabdoid muscle. When the rhabdoid muscle, such as myocardium and skeletal muscle, is injured, the creatine kinase isoenzyme will be released into the blood, and it will start to rise in 4-6 hours, the peak time is 24 hours, and the recovery time is 48-72 hours.

CK-MB performance index

CK-MB Clinical significance

• AMI was diagnosed early and risk stratified
• Estimate infarct size or reinfarct size
• The most valuable marker of MI is non-ST elevation

CK-MB Clinical value

The isozyme of creatine kinase plays an important role in clinical diagnosis. The level of creatine kinase in human serum increases rapidly during the occurrence of various diseases including muscle atrophy and myocardial infarction. It is believed that the activity of creatine kinase can be measured more reliably than electrocardiogram in the diagnosis of myocardial infarction. In myocardial infarction, creatine kinase is elevated within 6 hours of onset, peaks at 24 hours, and returns to normal within 3-4 days. Among them, the creatine kinase isoenzyme CK-MB has the highest diagnostic specificity. Creatine kinase has attracted extensive attention and in-depth research because of its important physiological function and clinical application value

CK-MB Normal value

1. Electrophoretic method: CK-MB<0.05 (CK-MB<5%) CK-MM>0.94 ~ 0.96 (CK-MM>94% ~ 96%) CK-BB no or trace (CK-BB no or trace)
2. Enzyme rate method (37℃) CK-MB: 0 ~ 18U/L CK-MM: 0 ~ 18U/L CK-BB: 0U/L.

Application Department

Cardiology, emergency, laboratory, pediatrics, hematology, oncology, Nephrology, surgery, etc

CK-MB Clinical comparison

MYO Clinical Comparison

Company profile

Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise engaged in the research and development, production and operation of in vitro diagnostic products. The in vitro diagnostic products developed by the company cover POCT series, microbial series, biochemical series and immune series reagents and supporting instruments.
The company has always adhered to the core concept of "fast and accurate, living up to life", committed to providing society with excellent products and services, and contributing to the cause of human health.