Keypath p16 Immunoassay Test Kit(ICC)
Intended Use
Keypath p16 Immunoassay Test Kit(ICC) is used for immunohistochemical staining on the basis of routine staining
(such asHE staining), and provides diagnostic auxiliary information for doctors.
Principle
Based on the principle of specific binding between immunological antigen and antibody, the antibody is combined with enzyme-labeled chromogenic system to form a complex, and enzyme substrate (chromogenic agent) is added to make it chromogenic to locate and characterize the antigen to be detected. The location of cell staining is nucleus/cytoplasm.
There’s close relationship between p16 and cervical cancer.
Persistent HPV infection produces viral oncogenic protein E7, which binds to host cell PRB, releases transcription factor E2F, interferes with the cell cycle, and causes cells to continue to differentiate and develop precancerous lesions.
Components of Test Kit
p16 antibody reagent, PBST (20×), Antigen repair solution (50×), Blocker, Penetrant,
HRP labeked secondary antibody, Chromogenic solution A, Chromogenic solution B,
Hematoxylin restaining solution, Bluing solution, Instruction for Use
Staining Result
Importance of p16 detection
- Reduce referral rates for colposcopy and reduce overtreatment.
- Reduce workload, improve image reading efficiency, and reduce missed diagnosis rate.
Specification
- 25 tests/kit ,50 tests/kit ,100 tests/kit