Toothpaste mixing machine is composed of a multi-stage vacuum system, a slow mixing system, a high-speed dispersion system, a high-efficiency cooling system and a high-viscosity discharging system. It can be equipped with a bottom external circulation homogenization function (used for white toothpaste production to increase the fineness of the paste and Finish). According to the production habits in the industry, there are 700L, 1300L, 2500L and other capacities for toothpaste factories to choose.