0.85 μM PES Membranes Unsupported Film For Making PES Cartridge Filters

All raw materials used for membrane production were suitable for manufacturing pharmaceutical grade filters, and the production lines were designed and manufactured by a world-class membrane machine manufacturer. The operating conditions and procedures in the membrane manufacturing were computer controlled so that the membranes produced have precise pore sizes and desired mechanical and filtration performance properties.

The Lenge PES membranes are highly asymmetric with a distinct uniform integral retention layer. The membranes have a high surface porosity and gradually increased pore size distribution in the direction facing upstream of filtration. The Lenge PES membrane filters have the following distinguished characteristics:

· High flux

· High capacity

· High mechanical strength

· High porosity

· Low leaching

The validation of bacterial B. diminuta retention for 0.22 µm rated pharmaceutical grade cartridges was performed in accordance with American Society of Testing and Materials (ASTM) method F838-05. Using this test methodology, 0.22 µm rated pharmaceutical grade filters retained greater than 1 x 10⁷ CFU of B. diminuta per cm² of effective filter surface area.

Features and Benefits

• Complies with United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88> for biosafety, cytotoxicity, and hemolysis testing.
• Hydrophilic membrane that wets out quickly and completely resulting in fast filtration with superior flow rates and high throughputs. Easily wet for reliable integrity testing.
• Compatible with EtO, gamma irradiation, and SIP/autoclave methods of sterilization.

Sealing methods

• Mechanical
• Ultrasonic
• RF welding

LENGE Membrane VS Some Other Brand Membrane

SEM micrograph for Surface of PES Microporous Membrane (0.22 µm)

LENGE Membrane Some Brand Membrane

Shown at 5000X magnification

Comments: LENGE Membrane Has More and Smaller Microporous Than Some Brand Membrane.

Dirt Holding Capacity Test - 0.22 µm PES Membrane by PVP

Test by Fermentation Broth

Dirt Holding Capacity Test - 0.22 µm PES Membrane by Fermentation Broth

Comments: 3M Vmax= 2500 L/m2; LENGE Vmax= 10000 L/m2

Bubble Point Consistency - 0.22 µm PES filter cartridges