Customized Mouse Anti ENO2 Monoclonal Antibody
Cat.No. BT-MCA0539 Size: 20ul/50ul/100ul Datasheet Request
Product Information
Clonallity: Monoclonal
Applications: WB, IHC, IF, ELISA
Source: mouse
Isotype: IgG
Protein Name: NSE
Immunogen: NSE fusion protein
Calculated molecular weight: 47kDa
Synonyms: ENO2, Enolase 2, enolase 2 (gamma, neuronal), Gamma enolase, Neural enolase, Neuron specific enolase, NSE
Species specificity: human, mouse, rat
Recommended Dilution:
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Store at 4°C for a month, for one year store at -20°C. When reconstituted in sterile pH 7.4 0.01 M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-20°C. Avoid repeated freeze/thaw cycles.
Background
NSE, also named as ENO2, belongs to the enolase family. Enolases are cytoplasmic glycolytic enzymes that may be involved in differentiation. The enolase has three isoenzymes, alpha, beta and gamma. The alpha form is expressed in most tissues, whereas the beta form is expressed in muscle tissue. The gamma enolase (ENO2), a homodimer, is primarily localized in neurons and neuroendocrine cells and is a cancer diagnostic marker for brain tumors. ENO2 plays a role in the glycolysis-related energy pathway and might be involved in higher metabolic activity during the day than at night, at least in part.