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Pharma Grade Alumina Grinding Balls Ceramic Milling Media GMP Compliant For Drug Manufacturing

Specifications

Brand Name :

Zhongli

Model Number :

AGB-01

Certification :

CE ISO

Place of Origin :

China

MOQ :

1kg

Supply Ability :

40-200ton per month

Delivery Time :

within 15 days

Packaging Details :

plastic + barrel

Shape :

Spherical

Density :

3.6-3.8 g/cm3

Packing :

25kg/bag or 1 ton/jumbo bag

Application :

Grinding and milling of ceramic, glass, and mineral materials

Chemical Composition :

Al2O3 ≥92%

Color :

White

Abrasion Resistance :

≤0.01%

Water Absorption :

≤0.01%

Crushing Strength :

≥2000N

Material :

Alumina

Size :

1mm-50mm

Hardness :

9 Mohs

Description

Product Description

Pharma Grade Alumina Balls: GMP-Compliant Solutions for Drug Manufacturing

Name: Pharma Grade Alumina Grinding Balls Ceramic Milling Media GMP Compliant For Drug Manufacturing
Brand: Zhongli
Price: 1 USD

In the ever-evolving pharmaceutical industry, precision and quality are paramount. One of the critical components in this sector is the use of high-purity materials that comply with Good Manufacturing Practices (GMP). Among these materials, pharma grade alumina balls have emerged as a vital element in drug manufacturing processes.

Understanding Pharma Grade Alumina Balls

Pharma grade alumina balls are high-density ceramic balls made from aluminum oxide (Al2O3). Known for their exceptional chemical resistance and ability to withstand high temperatures, these balls are engineered to meet the stringent purity and performance standards required in pharmaceutical applications. The alumina purity can range from 75% to 99.5%, depending on the specific needs of the application.

Why GMP Compliance Matters

Good Manufacturing Practices (GMP) are guidelines that ensure products are consistently produced and controlled according to quality standards. In drug manufacturing, GMP compliance is crucial to ensure the safety, efficacy, and quality of pharmaceutical products. Using GMP-compliant alumina balls ensures that the grinding and milling processes do not introduce impurities or contaminants into the final product.

Applications of Pharma Grade Alumina Balls in Drug Manufacturing

Grinding and Milling: Alumina balls are used in high-intensity stirred mills for fine and ultra-fine grinding processes. Their high density and hardness make them ideal for achieving the desired particle size and homogeneity in pharmaceutical powders.
Mixing and Dispersing: These balls are essential in mixing and dispersing active pharmaceutical ingredients (APIs) with excipients, ensuring uniform distribution and consistency in drug formulations.
Purity Maintenance: In critical applications where purity is paramount, alumina balls help maintain a pristine grinding environment by minimizing contamination and preventing chemical reactions with the processed materials.
Laboratory Equipment: Alumina ceramics are used in the production of laboratory equipment due to their excellent chemical resistance and durability, ensuring reliable performance in various experimental setups.

Advantages of Using Pharma Grade Alumina Balls

High Purity: With purity levels of up to 99.5%, pharma grade alumina balls ensure minimal contamination and maintain the integrity of pharmaceutical products.
Durability and Wear Resistance: These balls are engineered to withstand rigorous grinding environments, reducing the need for frequent replacements and ensuring sustained performance.
Chemical Inertness: Alumina balls are chemically inert, non-toxic, and non-magnetic, making them suitable for sensitive pharmaceutical applications.
Versatile Applications: Beyond pharmaceuticals, alumina balls are used in ceramics, mining, and other industries, highlighting their versatility and reliability.

●Chemical Composition:

Composition	Al₂O₃	SIO₂	CaO+MgO	Fe₂O₃
Wt%	≥92	7 max	≤2	＜0.1

●Typical Properties:

Specific Gravity

g/cm³

Bulk Density kg/L

Hardness

Moh’s

Water Absorption

Self wearing loss %(24hrs)

Compression

Mpa

≥3.65

≥2.2

＜0.01

≤0.012

≥2000

● Sizes Φ:

Size(mm)	Size(mm)	Size(mm)	Size(mm)
0.5-1.0	6.0	20.0	70.0
1.0	8.0	25.0	80.0
2.0	10.0	30.0	90.0
3.0	13.0	40.0	100.0
4.0	15.0	50.0
5.0	18.0	60.0

1. Mechanical & Physical Properties

Property	Alumina (92%)	Alumina (99%)	Zirconia	Steel	Silica Sand
Density (g/cm³)	3.6	3.9	6.0	7.8	2.2
Hardness (Mohs/HV)	9 (~1,500 HV)	9 (~1,800 HV)	8.5	6-7	7
Wear Rate (g/ton)	10–50	5–20	1–5	100+	300+
Compressive Strength	2,000 MPa	2,500 MPa	2,200 MPa	500 MPa	Low

Key Takeaways:

99% Alumina offers 30% lower wear than 92% grade.
2–5x longer lifespan vs. steel in abrasive slurries.
Harder than zirconia but less tough (ideal for fine grinding).

2. Chemical & Thermal Resistance

Property	Alumina (99%)	Performance Impact
Chemical Inertness	Resists pH 1–14	Safe for acids/alkalis, pharmaceuticals.
Max Temperature	1,600°C	Stable in kilns, calcination.
Thermal Shock	Moderate	Avoid rapid quenching (>200°C/min).
Contamination Risk	None	Zero metal ions (critical for Li-ion batteries).

Vs. Competitors:

Beats steel in corrosion resistance.
Outperforms silica sand in wear & consistency.

3. Grinding Efficiency

Particle Size Reduction: Achieves sub-micron fineness (D50 < 1µm) in wet/dry mills.
Speed: Higher density (vs. silica) improves kinetic energy transfer.
Consistency: Uniform shape/size prevents clogging in bead mills.

Best For:

High-purity materials (e.g., ceramics, electronics powders).
Slurry processing (paints, dyes).

4. Industry-Specific Performance

Industry	Benefit of Alumina Balls
Mining	50% lower replacement cost vs. steel in ore grinding.
Pharma	FDA-compliant, no endotoxin release.
Batteries	Prevents Fe/Ni contamination in cathode materials.
Paints	Maintains color purity (no metal leaching).

5. Cost vs. Lifetime Analysis

Media Type	Cost per kg	Lifespan (hours)	Cost per Ton Ground
Alumina (92%)	$5–10	2,000–3,000	$0.50–1.00
Steel	$2–4	500–800	$2.00–4.00
Zirconia	$50–100	5,000+	$0.20–0.50

Trade-Off:

Alumina balances cost and performance – Ideal when zirconia is over-spec.

Performance Summary: Why Choose Alumina?

✅ Cost-Effective: 3x cheaper than zirconia for moderate abrasion.
✅ High-Purity: 99.9% Al₂O₃ for sensitive applications (e.g., pharma).
✅ Versatile: Works in ball/attritor/planetary mills.
✅ Low Maintenance: Non-corrosive, easy to clean.

Limitations:

Not for high-impact milling (e.g., hammer mills).
Thermal shock risk in rapid cooling applications.

Need Custom Alumina Balls?

We supply:

Sizes: 1mm–50mm (±0.01mm tolerance).
Grades: 92%, 95%, 99%, ZTA-composite.
Certifications: ISO 9001, RoHS, FDA (for pharma).

●Package:

25KG/woven bag,1000KG-1250KG for one pallet with shrink wrapped