Sperm-Hyaluronan Binding Assay kit, a diagnostic tool for Male fertility
Hyaluronan (HA), a high molecular weight glycosaminoglycan, is a major component of the cumulus oophorus
matrix surrounding the human oocyte. Within the female reproductive tract, hyaluronan is believed to play a
critical role in the selection of functionally competent sperm during fertilization. In fact only mature spermatozoa
that have completed the plasma membrane remodelling, cytoplasmic extrusion and nuclear maturation have
developed specific receptors for hyaluronan. Only these mature sperm with receptors can bind to the cumulus
complex, digest HA and reach the oocyte and fertilize it.
Intended use:
The major usage of this kit is for evaluating the maturity of motile spermatozoa. It could provide a qualitative
assessment of sperm quality, maturity, and fertilizing potential.
Features: