SpermFunc® DNAf -Kit for Determination of the DNA Fragmentation Level in Spermatozoa (Sperm Chromatin Dispersion Method)

It was reported that the rate of abortion caused by sperm DNA fragmentation was higher than other factors in the process of IVF or ICSI treatment.

Studies have shown that sperm DNA fragmentation may result from the aberrant assembly of chromosome and excessive production of reactive oxygen species (ROS) or pathological apoptosis. Fertilization by fragmented -DNA sperm may cause sterility, habitual abortion and lower pregnancy rate in Assisted Reproductive Technology (ART) treatment.

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Features:

• The reagent kit has excellent staining for sperm, easy to identify the fragmented sperm. The head halo of non-fragmented sperm is large, and the boundary between the head and halo is obvious.
• Various appliances outfitted in the kit, easy to operate.
• Quick operating within one hour, the result is observed under the ordinary microscope without any other special instrument, easy to apply in clinic.
• 40T/Kit. Economical price but more efficient than the competitive products in the market.
• Made by the special advanced technics, the reagents are stable and reliable with a shelf life of two years.
• The unique preservable technology for specimen makes it possible that the specimen stored for at least 15 days, which can reproduce results as the fresh one. It is great for testing in batch in clinic.
• CE approved

Test principle:

The testing principle of SpermFunc^® DNAf is based on SCD

method (Sperm ChromatinDispersion Method), which evaluates

the levels of sperm DNA fragmentation by the size of the halo
and (or) the presence or not. SpermFunc^® DNAf can be helpful
in the pathogenesisanalysis in infertility and natural abortion and

the inactive development of embryo. It is of important clinical

significance in the selection of ART method and the forecast of
pregnancy outcome to test sperm DNA fragmentation by

SpermFunc^® DNAf.

Indications for use of the SpermFunc^® DNAf:

• With history of spontaneous abortion
• All males in infertility exceeded six month or one year
• Intended for IUI, IVF and ICSI
• Males of more than 40 years old
• The male smoker
• The drug addicts
• The patients in cancer therapy
• People exposed to noxious conditions
• The infection of genitourinary system
• Intended for varicocelectomy