Specifications
Brand Name :
New Life
Model Number :
N/M
Certification :
ISO13485,CE
Place of Origin :
China
MOQ :
5mg
Payment Terms :
T/T, Western Union
Supply Ability :
2001mg/month
Delivery Time :
10-35days
Packaging Details :
0.5mg/tube 1mg/tube, 2mg/tube、5mg/tube、10mg/tube、20mg/tube、30mg/tube
Category :
Mouse Monoclonal Antibody
Application :
Anti-COT raw material
Usage :
Rapid Diagnostic test
Specimen :
Urine
Shelf Life :
12 months
Description

Purified Anti-Cotinine Mouse Monoclonal Antibody 3.91mg/mL

Background:

Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans. Nicotine is a drug to which virtually every member of a tobacco-smoking society is exposed whether through direct contact or second-hand inhalation. In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies such as nicotine gum, transdermal patches and nasal sprays. In a 24-hour urine, approximately 5% of a nicotine dose is excreted as unchanged drug with 10% as cotinine and 35% as hydroxycotinine; the concentrations of other metabolites are believed to account for less than 5%.1 While cotinine is thought to be an inactive metabolite, it’s elimination profile is more stable than that of nicotine which is largely urine pH dependent. As a result, cotinine is considered a good biological marker for determining nicotine use. The plasma half-life of nicotine is approximately 60 minutes following inhalation or parenteral administration.2 Nicotine and cotinine are rapidly eliminated by the kidney; the window of detection for cotinine in urine at a cutoff level of 200 ng/mL is expected to be up to 2-3 days after nicotine use. The COT One Step Cotinine Test Device (Urine) is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of Cotinine in urine. The COT One Step Cotinine Test Device (Urine) yields a positive result when the Cotinine in urine exceeds 200 ng/mL.

Specification:

Clonality Monoclonal
Isotype IgG1
Host Host: Mouse
Source: Ascites
Specificity Cotinine
Purity/Purification DEAE chromatography
Form/Format Purified, Liquid
Concentration 3.91 mg/ml (lot specific)
Immunogen Cotinine-BSA
Affinity Constant Not determined
Buffer 15mM phosphate, pH 7.2 containing 0.85% Sodium chloride
Preservative NaN3. 0.05% Sodium azide
Warning This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Preparation and Storage Store at 2-8 degree C.
ISO Certification Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes Small volumes of anti-Cotinine antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.


Anti-Cotinine Mouse Monoclonal Antibody Purification 3.91mg/mL

ORIENT NEW LIFE MEDICAL CO., LTD.
Contact: Jerry Meng
Email: Jerry @ newlifebiotest .com
Tel. +86 18657312116
SKYPE enetjerry
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Anti-Cotinine Mouse Monoclonal Antibody Purification 3.91mg/mL

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Brand Name :
New Life
Model Number :
N/M
Certification :
ISO13485,CE
Place of Origin :
China
MOQ :
5mg
Payment Terms :
T/T, Western Union
Contact Supplier
Anti-Cotinine Mouse Monoclonal Antibody Purification 3.91mg/mL
Anti-Cotinine Mouse Monoclonal Antibody Purification 3.91mg/mL

Orient New Life Medical Co.,Ltd.

Active Member
9 Years
zhejiang, ningbo
Since 2009
Business Type :
Manufacturer, Exporter
Total Annual :
10,000,000-15,000,000
Employee Number :
200~300
Certification Level :
Active Member
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