Carbomer Model 1342: Pharmaceutical Grade Precision Controlled Release Carrier, Excellent Biocompatibility Partner, Open A New Journey Of Targeted Medicine Delivery

Basic product introduction:

• Carbomer 1342 is a polymer of acrylic acid bond and allyl sucrose or pentaerythritol allyl, also known as polyacrylic acid, carboxyvinyl copolymer.
• Its appearance is white loose powder, slightly special odor, strong hygroscopicity, soluble in ethanol, water and glycerol, the molecular structure contains 52%-68% carboxylic acid group, is weakly acidic.
• After being ionized by the neutralized carboxyl group, the molecular chains disperse and stretch into a greatly expanded state, and have viscosity, which can form a clarified viscous gel.

Product features:
-- Physical properties
1. Solubility

• It has good water solubility, can be quickly dispersed in water and self-wetting.

2. Appearance and form

• It is a white loose powder with strong hygroscopicity.

3. Transparency

• With high transparency, can make the product more clear and transparent.

4. Viscosity

• It provides medium to high viscosity and maintains a relatively stable viscosity over a wide pH range.

-- Chemical properties
1. Stability

• It has good chemical stability, can withstand the action of acid, alkali, solvent and other chemical substances, and is not easy to melt or decompose at high temperatures.

2. Electrolyte resistance

• It can be used in systems containing moderate surfactants to provide electrolyte resistance to formulations that maintain viscous, transparent and stable properties even in environments containing electrolytes.

3. Antioxidant properties

• It has certain antioxidant properties, can trap free radicals, slow down skin oxidation reaction, and help delay skin aging.

Product application field:
1. Medical field

• Carbomer eye drops and eye gel can be used as a substitute for tears to treat dry eyes. By forming a transparent crystal gel with high viscosity and sticking to the surface of the cornea to store liquid, it can relieve dry eyes and other symptoms.
• In the pharmaceutical industry, carbomer is often used as an excipient for the manufacture of ointment, gel, suppository and other dosage forms, which can improve the stability of medicine, control medicine release, and enhance the efficacy of medicine.

2. Cosmetics

• In creams and lotions, carbomer acts as a thickener and emulsifier to increase product viscosity, improve texture, and prevent ingredient separation.
• When used in shampoos and conditioners, it helps to mix oil-soluble and water-soluble ingredients and maintain the texture and stability of the product.
• In gel products, transparent and high-viscosity gel systems can be formed, such as facial washing gel, eye gel, etc.
• In addition, it can also be used as a film forming agent to form a thin film on the skin surface to reduce water evaporation and play a moisturizing effect, and can also be used as a controlled release carrier to control the release rate of active ingredients and extend the action time of the product.

3. Oral care

• Carbomer can be used to prepare products such as toothpastes, oral mouthwashes and oral sprays, providing the right viscosity and texture and keeping the ingredients stable.

Advice:

• Recommended usage is 0.2~1.5wt %, while stirring the polymer evenly scattered in the medium, but to avoid agglomeration, fully stirred to disperse, and to pH 7.0~10 polymer has ideal thickening performance, after neutralization should avoid high-speed shear or stirring to reduce viscosity loss.

Using Tips:

• After carbomer completely dissolves water, it needs to add alkaline substances to neutralize to achieve good results, such as triethanolamine, sodium hydroxide and so on.