Name | Piroxicam-beta-cyclodextrin complex |
Synonyms | Cycladol |
Molecular Formula | C42H70O35.xC15H13N3O4S |
CAS Registry Number | 96684-39-8 |
Appearance: light yellow powder, odorless and tasteless
Ammonia≤0.5%
2- amino pyridine≤0.03%
Free content≤0.5%
Loss on drying ≤10%
Piroxicam content9.73-11.1%
Characteristics and applications:
A kind of piroxicam belongs to non steroidal anti-inflammatory drugs, anti-inflammatory effects, but insoluble in water, slowly absorbed, leading to gastrointestinal bleeding and gastric ulcer easily after oral administration, intramuscular injection may cause mild pain at the injection site and tissue necrosis. Piroxican preparation of piroxicam beta cyclodextrin (piroxicam- beta -cyclodextrin) inclusion compounds, can accelerate the dissolution rate, reduce the irritation of the gastrointestinal tract. Oral analgesics like to pass (Cycladol) for piroxicam beta cyclodextrin inclusion complexes of the successful application.
Piroxicam beta - cyclodextrin (also known as inflammatory pain oxicam betacyclodextrin) is a company with new unique technology, according to a certain proportion of the pharmaceutical grade of piroxicam and pharmaceutical grade betacyclodextrin inclusion is refined, the inclusion complexes with piroxicam monomer compared with less odor, more stability and more stable drug release rate, mainly used in anti-inflammatory analgesic drugs ointment.