PO Nanofiber Membrane Chromatography Syringe Remove DNA HCPs Endotoxins 25mm 0.45μM Pharmaceutical Industry MCQ Anion Ion Exchange Chromatography

Description Remove DNA HCPs Endotoxins

Ion exchange chromatography is a technique for separating compounds based on their net charge. Ion exchange chromatography media contain negatively or positively charged functional groups covalently bound to a solid support, yielding either a cation or anion exchanger, respectively. Charged compounds are adsorbed and retained by an ion exchanger having the opposite charge, whereas compounds that are neutral or have the same charge as the media pass through the void volume and are eluted from the column. The binding of the charged compounds is reversible, and adsorbed compounds are commonly eluted with a salt or pH gradient. Ion exchange media are available in various particle sizes, ionic forms, and purity ranges.

Application Remove DNA HCPs Endotoxins

• Capture large particles such as recombinant proteins, plasmids, viruses, viral vectors and plasma components;
• Polishing steps to remove contaminants such as host DNA, HCPs, and endotoxins in biological fluids;
• Fine purification of small molecule drugs such as oligonucleotides and peptides.

Features Remove DNA HCPs Endotoxins

• Materials to clarify both aqueous and mild organic solutions;
• 100% passed integrity test;
• Low-binding membrane;
• Low IC extractables;
• Ethylene oxide or gamma irradiation sterilization;
• Ready to use equipment;
• Easy to connect Syringe Filter or Pump;
• High adsorption capacity to macromolecule;
• High flow rate and high capacity;
• Well developed separation function.

Filter Performance Remove DNA HCPs Endotoxins

Naming Regulations Remove DNA HCPs Endotoxins