Thymidine Kinase (TK1)

Thymidine kinase 1 (TK1), a special kinase that catalyzes thymidine (TdR) to 1-phosphothymidylate (TMP), is an essential precursor for DNA synthesis in cancerous cells.

1. TK1 is a cell cycle-dependent enzyme that mainly exists in the cytoplasm. When a large number of proliferating cells appear in the body, the level of TK-1 increases ly. Once canceration occurs, along with the proliferation of tumor cells, the activity and content of TK-1 will increase, which can exceed the normal level by 20-100 times.

2. TK1 (cytoplasmic thymidine kinase 1) is an internationally recognized marker of abnormal cell proliferation. It can detect the level of thymidine kinase 1 (STK1) in serum, dynamically understand the proliferation activity information of cancer cells in vivo, and evaluate the therapeutic effect of tumors. , an earlier predictor of tumor recurrence risk. Mainly used for: evaluating the effect of surgery, monitoring the effect of chemotherapy, predicting the risk of recurrence, and judging tumor prognosis, etc.

3. The application of TK1 to evaluate the effect of surgery. Scope of application: tumor surgery of various parts. Recommended monitoring points: 3 days or the same day before surgery, 7 days after surgery; before discharge, or 30 days after surgery, and before starting other treatments.


EXPLANATION OF THE TEST


TK1 is a cell cycle-dependent enzyme, mainly present in the cytoplasm. When a large number of proliferating cells appear in the body, the level of TK-1 increases ly. Once canceration occurs, along with the proliferation of tumor cells, the activity and content of TK-1 will increase, which can exceed the normal level by 20-100 times.

TK1 (cytoplasmic thymidine kinase 1) is an internationally recognized marker of abnormal cell proliferation. It can detect the level of thymidine kinase 1 (STK1) in serum, dynamically understand the proliferation activity information of cancer cells in vivo, evaluate the therapeutic effect of tumors, and more. early predictor of tumor recurrence risk. Mainly used for: evaluating the effect of surgery, monitoring the effect of chemotherapy, predicting the risk of recurrence, and judging tumor prognosis, etc.

Application of TK1 to assess surgical outcomes. Scope of application: tumor surgery of various parts. Recommended monitoring points: 3 days or the same day before surgery, 7 days after surgery; before discharge, or 30 days after surgery, and before starting other treatments.

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