Specifications
Brand Name :
Zecen
Model Number :
HBeAb
Certification :
CE, ISO13485
Place of Origin :
China
MOQ :
1
Price :
Negotiable
Payment Terms :
L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability :
5000 Set/Sets per Month
Delivery Time :
15 workdays
Packaging Details :
Carton package
Name :
HBeAb/HBeAg
Analyzer :
CLIA series
Luminescent markers :
AP(alkaline phosphatase)
Calibration :
2-points
Calibrator :
Free
Quality Control :
Free
Storage :
2-8°C
Material :
Magnetic beads, calibrators, Anti A/B, controls
Validity period :
18 months
Precision :
≤8%
Description

Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb)

HBeAg and Antibodies

Hepatitis B e antibody is a soluble viral protein. It is found early in the course of acute hepatitis B and disappears soon after ALT peaks. Persistence of HBeAg beyond 3 months after the onset of illness is unusual and may suggest progression to chronic infection.

In patients with chronic hepatitis B, the presence of positive HBeAg usually indicates a high level of viral replication and thus infectivity. HBeAg is positive in the immune tolerant phase and in the early immune clearance phase. HBeAg seroconversion is the disappearance of HBeAg and appearance of hepatitis B e antibody (anti-HBe). Most patients enter the inactive HBsAg carrier state after HBeAg seroconversion (Fig. 30-4). This state is associated with low HBV DNA, normal ALT, and little hepatic necroinflammation. However, some patients continue to have active liver disease and detectable serum HBV DNA. This can be due to either a wild-type virus or the presence of precore stop codon mutation and/or basal core promoter mutations that impair HBeAg secretion.9

HBe-AbAg: when present, especially without HBeAb, suggests increased patient infectivity.

HBeAb-total: when present, suggests less patient infectivity.

I.

HBSAg positive, HBCAb negative*

About 5% (range 0%-17%) of patients with early-stage HBV acute infection (HBCAb rises later)

II.

HBSAg positive, HBCAb positive, HBSAb negative

a.

Most of the clinical symptom stage

b.

Chronic HBV carriers without evidence of liver disease (“asymptomatic carriers”)

c.

Chronic HBV hepatitis (chronic persistent type or chronic active type)

III.

HBSAg negative, HBCAb positive,* HBSAb negative

a.

Late clinical symptom stage or early convalescence stage (core window)

b.

Chronic HBV infection with HBSAg below detection levels with current tests

c.

Old previous HBV infection

IV.

HBSAg negative, HBCAb positive, HBSAb positive

a.

Late convalescence to complete recovery

b.

Old infection

Clinical significance
(1) Chronic hepatitis B HBeAb positive accounted for 48.3%, liver cirrhosis was 68.3%, and liver cancer was 80%.
(2) The positive rate of HBeAb increased, indicating that most patients were infected with hepatitis B virus for up to 7-27 years.
(3) HBeAb positive will still be infectious to a certain extent. 20% of babies born to HBeAb-positive pregnant women are infected with hepatitis B virus.

Test Item HBeAb
Luminescent Principle Enzymatic chemiluminescence
Luminescent Markers AP(alkaline phosphatase)
Specification 100/50 Tests/Kit
/
Principle Sandwich method
Component Magnetic Beads
Calibrator Low
Calibrator High
Anti-A/Anti-B
Control 1
Control 2
Accessories Required But Not Provided Substrate
Washing solution
Sample material Serum
Storage 2-8℃


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Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb)

Ask Latest Price
Brand Name :
Zecen
Model Number :
HBeAb
Certification :
CE, ISO13485
Place of Origin :
China
MOQ :
1
Price :
Negotiable
Contact Supplier
Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb)
Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb)
Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb)
Infectious disease diagnostic kit for closed chemiluminescent immunoassay analyzer Hepatitis B e antibody (HBeAb)

Taizhou Zecen Biotech Co.,Ltd.

Active Member
3 Years
jiangsu, taizhou
Since 2011
Business Type :
Manufacturer
Employee Number :
300~500
Certification Level :
Active Member
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